dna cleavage and anti-proliferative activity of cox-2 inhibitor derivatives on human breast adenocarcinoma and chronic myeloid leukemia cells
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چکیده
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Cytotoxic and anti-proliferative effects of Rosa beggeriana Schrenk extracts on human liver and breast cancer cells
Objective: Rosa beggeriana Schrenk has been consumed in Iranian traditional medicine. In contrary to its close species (e.g. R. canina), there is no data on its medicinal properties. Therefore, we explored possible cytotoxic effects of R. beggeriana against two cancer cell lines. Materials and Methods: The cytotoxic and anti-pro...
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Objectives: Ziziphus Jujube (Jujube) plant has exhibited numerous medicinal and pharmacological properties including antioxidant and anti-inflammatory effects. This study was carried out to investigate its anti-cancer and pro-apoptotic abilities in human cervical and breast cancer cells in vitro. Materials and Methods: The cervical OV2008 and breast MCF-7 cancer cells were incubated with differ...
متن کاملa study on the dna cleavage, morphological changes and cytotoxicity activities of the two synthetic cox-2 inhibitors
celecoxib, a specific cyclooxygenase-2 (cox-2) inhibitor, has been shown to possess antitumor activity in a variety of cancer cells. however, the antitumor activity of two synthesized cox-2 inhibitor derivatives ( a and b ) on human myeloid leukemia (k562) and breast adenocarcinoma (mcf-7) cancer cells has not been well established. this study was designed to investigate the morphological chang...
متن کاملAntioxidant activity and Cytotoxicity Effect of Various Extracts of Sclerorhachis platyrachis on the Human breast adenocarcinoma Cells
Background and Aim: One of the spices of compositae is the Sclerorhachis platyrachis that is Iranian native. This aromatic plant has been known as bacterial growth inhibitor. This study have been attempted to investigate antioxidant activity and cytotoxicity effect of Sclerorhachis platyrachis extractson the MCF-7 cell line. Materials and Methods: The Hexane (HE), Chloroform (CE), Ethyl acetate...
متن کاملThe Comparison of Anticancer Activity of Thymoquinone and Nanothymoquinone on Human Breast Adenocarcinoma
Cancer is one of the main causes of mortality in the world which appears by the effect of enviromental physico-chemical mutagen and carcinogen agents. The identification of new cytotoxic drugs with low side effects on immune system has developed as important area in new studies of immunopharmacology. Thymoquinone (TQ), derived from the medicinal spice Nigella sativa (also called black cumin) ex...
متن کاملThe Comparison of Anticancer Activity of Thymoquinone and Nanothymoquinone on Human Breast Adenocarcinoma
Cancer is one of the main causes of mortality in the world which appears by the effect of enviromental physico-chemical mutagen and carcinogen agents. The identification of new cytotoxic drugs with low side effects on immune system has developed as important area in new studies of immunopharmacology. Thymoquinone (TQ), derived from the medicinal spice Nigella sativa (also called black cumin) ex...
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عنوان ژورنال:
research in pharmaceutical sciencesجلد ۷، شماره ۵، صفحات ۰-۰
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